

Pinealon / PE22-28 / Selank
Short regulatory peptides discussed in longevity and cognition circles; research is early and mostly preclinical.
| Concentration | 2 mg/2 mg/2 mg/mL (5 mL) |
| Vial total | 10/10/10 mg |
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About Pinealon / PE22-28 / Selank
The honest rundown
Straight information, no hype — so your conversation with a physician starts from the truth.
This blend combines short regulatory peptides — Pinealon and PE22-28 — with Selank, and comes up in longevity and cognition circles. The appeal is a research-forward, brain-and-aging-oriented stack.
The honest caveat: research on these is early and mostly preclinical, and the specific combination is essentially unstudied. A physician decides whether it fits your goals and history.
How it works
What the science actually looks at
Pinealon
A short regulatory peptide studied, largely preclinically, for neuro- and aging-related signaling.
PE22-28
A peptide fragment discussed in cognition and mood research, with early evidence.
Selank
Discussed for stress resilience and a calm-focus profile in the research where it's been studied.
Who it's for
Who tends to look into this
- People drawn to longevity- and cognition-oriented research
- Experienced users curious about a research-forward stack
- Anyone who wants a clinician to vet an early-stage combination
The approach
Possible duration & dosing
Duration
Typically used in cycles set by your physician.
How it's given
A subcutaneous injection.
Your dose
Your physician sets the dose and cycle length for the blend.
With every order
What's included
- A consultation with our physician-led team
- A doctor-reviewed medical history and a plan personalized to you
- Temperature-controlled shipping with tracking on every order
- Complete supplies — syringes, alcohol wipes, and clear instructions
- TCO Wellness supports you with messaging access and new orders
Realistic view
Possible expectations
The honest baseline
Research on these peptides is early and largely preclinical, and the combination is essentially unstudied — so keep expectations modest.
If you and your physician proceed
Any changes are subtle and individual, and are best judged over a full cycle.
Checking in
Your provider reviews how it's going and adjusts. Nothing here is guaranteed.
Keeping it right
Storage & handling
- Keep it cool and out of direct light — refrigerate unless your instructions say otherwise
- Follow the storage and handling directions that ship with your order
- If anything looks off — cloudy, discolored, or past date — check with your provider before using
- Dispose of any needles and syringes in a proper sharps container
Questions
Common questions
How proven is this?
Not very — research on these peptides is early and largely preclinical, and the combination itself is essentially unstudied. Expectations should be modest.
Are they FDA-approved?
No — they're compounded and not FDA-approved. A licensed physician decides whether they're appropriate for you.
How is it taken?
A subcutaneous injection on a physician-set protocol. Supplies and instructions are included with every order.
Before you ask
Worth knowing
- Research is early and mostly preclinical; the combination is essentially unstudied.
- The peptides are compounded and not FDA-approved.
- A physician decides candidacy and dosing.
- Available only after a doctor reviews your medical history.
How it's made
Quality & compliance
- Prescribed only by an independent licensed physician after reviewing your medical history
- Compounded and dispensed by a state-licensed 503A compounding pharmacy
- Prepared patient-specific — compounded medications are not FDA-approved products
- Backed by coaching and concierge support the whole way through
Often discussed alongside:Semax / Selank, for a more focus-oriented pairing
Educational information only — not medical advice, and not a claim of results. Whether any therapy is right for you, and at what dose, is determined solely by an independent licensed physician after reviewing your medical history.
How it works at TCO
No therapy is a product you simply buy
An independent licensed physician reviews your history and determines whether therapy is appropriate. Want to talk it through with the doctor directly? We'll set that up.If approved, your order is fulfilled by a state-licensed 503A compounding pharmacy with temperature-controlled shipping and every supply included — and you're coached throughout your journey.
Prescription products require an evaluation with a licensed medical professional, who will determine whether a prescription is appropriate. Compounded medications are prepared by a state-licensed 503A compounding pharmacy and are not FDA-approved; the FDA does not review compounded medications for safety or effectiveness.
TCO Wellness is a wellness and concierge-care company — we do not practice medicine. All prescriptions are issued by independent licensed physicians after review of your medical history, and medications are compounded and dispensed by a state-licensed 503A compounding pharmacy. Individual results vary.