Tirzepatide (B6/B12)
An FDA-approved active researched for weight management and metabolic health, with some of the largest effect sizes seen in modern obesity trials — compounded with B6/B12.
One-time $39 payment · Zero recurring subscription · 100% refund guarantee
- ✓ 60-min 1:1 founder consult (Vince or Sammie) + 30 days of text coaching
- ✓ Independent MD evaluation & transparent 503A pharmacy pricing reviewed on your call before you pay for any medication
- ✓ 100% Refund Guarantee on your $39 consult if you aren't medically eligible or decide not to proceed
- ✓ Ships cold-chain tracked from a licensed US 503A pharmacy with comfort supplies & 1:1 first-dose guidance included
What do full protocols cost after the $39 consult?▾
No hidden markups or $1,500 surprise packages: If an independent MD approves your protocol, orders combine transparent pass-through 503A pharmacy compounding + $39 MD review + $30 cold-chain shipping(with ultra-fine comfort syringes, alcohol wipes & step-by-step administration coaching included).
Depending on compound and physician-prescribed strength, most monthly protocols average $150–$350/mo, and nothing is ever billed without your explicit go-ahead after your consult.
The active ingredient is FDA-approved. This compounded formulation is not FDA-approved; the FDA does not review compounded medications for safety or effectiveness.
| Concentration | 5–30 mg/0.5 mg/1 mL (2 mL vial) |
Available strengths
- 2.5 mg dose · 10 mg
- 5.0 mg dose · 20 mg
- 7.5 mg dose · 30 mg
- 10 mg dose · 40 mg
- 12.5 mg dose · 50 mg
- 15 mg dose · 60 mg
- 3-month bundle · months 1–3 · 60 mg total
- 3-month bundle · months 4–6 · 150 mg total
Your physician determines the appropriate strength and titration.
About Tirzepatide (B6/B12)
The honest rundown
Straight information, no hype — so your conversation with a physician starts from the truth.
Tirzepatide is a dual GIP/GLP-1 receptor agonist — one molecule that engages two of the body's appetite- and blood-sugar-regulating pathways at once. Its active ingredient has been studied in large, modern human trials, where it produced some of the biggest effect sizes seen in obesity and metabolic research.
The partner 503A pharmacy compounds it with B6 and B12. It's a serious, physician-managed therapy — not a shortcut — and it works best alongside the nutrition, training, and coaching that make results last. A licensed physician decides whether it's right for you and owns your dose and titration schedule.
How it works
What the science actually looks at
GLP-1 pathway
Like semaglutide, it acts on GLP-1 receptors tied to satiety and hunger signaling.
GIP pathway
It also engages GIP receptors — the second pathway researchers credit for its larger effect sizes in trials.
Gastric emptying
It slows stomach emptying, which is studied for its role in feeling satisfied longer.
B6 / B12
The pharmacy's formulation adds B6 and B12, vitamins some providers pair with GLP-1 therapy.
Who it's for
Who tends to look into this
- People pursuing significant, medically-supervised weight loss
- Those who've plateaued on diet, exercise, or a prior GLP-1
- Anyone who wants coaching and accountability alongside therapy
- Candidates ready for a doctor-reviewed, longer-term plan
The approach
Possible duration & dosing
Duration
A longer-term therapy your physician reviews over time — not a quick course.
How it's given
A once-weekly subcutaneous injection.
Your dose
Your physician starts low and steps the dose up gradually. The schedule is theirs to set — never self-adjusted.
With every order
What's included
- A consultation with our physician-led team
- A doctor-reviewed medical history and a plan personalized to you
- Temperature-controlled shipping with tracking on every order
- Complete supplies — syringes, alcohol wipes, and clear instructions
- TCO Wellness supports you with messaging access and new orders
Realistic view
Possible expectations
The honest baseline
Tirzepatide produced some of the largest effects in modern trials, but trial averages aren't a promise for any one person.
Early weeks
As the dose is titrated up, reduced appetite is the common early signal — with digestive side effects possible alongside it.
Over the months
Body-composition and metabolic changes tend to unfold over months, and lifestyle still does much of the work. No outcome is guaranteed.
Keeping it right
Storage & handling
- Keep it cool and out of direct light — refrigerate unless your instructions say otherwise
- Follow the storage and handling directions that ship with your order
- If anything looks off — cloudy, discolored, or past date — check with your provider before using
- Dispose of any needles and syringes in a proper sharps container
Questions
Common questions
How is it different from semaglutide?
Tirzepatide works on two receptors (GIP and GLP-1) rather than one, which is linked to larger effect sizes in trials. Which one suits you is a question for your physician.
Is it the same as Mounjaro or Zepbound?
Same active ingredient, but the version available through TCO programs is a compounded B6/B12 formulation from a state-licensed 503A pharmacy — not the branded, FDA-approved product.
What about side effects?
Digestive effects are most common, particularly early and when stepping up a dose — a normal part of the physician conversation.
How is it taken?
A once-weekly subcutaneous injection at a physician-set dose. Syringes, alcohol wipes, and instructions ship with every order.
Before you ask
Worth knowing
- The active is FDA-approved; the pharmacy-compounded B6/B12 version is not FDA-reviewed.
- Not for use in pregnancy, or with a personal or family history of medullary thyroid cancer or MEN2 — tell your physician.
- Dosing steps up gradually and is owned by your provider, never self-managed.
- Best paired with the nutrition and coaching included in every program.
How it's made
Quality & compliance
- Prescribed only by an independent licensed physician after reviewing your medical history
- Compounded and dispensed by a state-licensed 503A compounding pharmacy
- Prepared patient-specific — compounded medications are not FDA-approved products
- Backed by coaching and concierge support the whole way through
Educational information only — not medical advice, and not a claim of results. Whether any therapy is right for you, and at what dose, is determined solely by an independent licensed physician after reviewing your medical history.
Explore Similar Protocols
Other options in Weight Loss
Semaglutide (B6/B12)
1–10 mg/0.5 mg/1 mL (1 mL vial)
An FDA-approved active studied extensively for appetite regulation, blood-sugar control, and weight management in large human trials — compounded with B6/B12.
View protocol
Lipo-B (MICB)
25/50/50/1 mg/mL (10 mL vial)
A vitamin–amino acid blend used in wellness settings to support normal fat metabolism and energy; evidence is modest and supportive rather than dramatic.
View protocolHow it works at TCO
Ready when you are
Start with a $39 online consult. If this therapy is a fit, Vince or Sammie will walk you through next steps — including a physician review. Compounded medication, if prescribed later, ships from a licensed 503A pharmacy.
Prescription products require an evaluation with a licensed medical professional, who will determine whether a prescription is appropriate. Compounded medications are prepared by a state-licensed 503A compounding pharmacy and are not FDA-approved; the FDA does not review compounded medications for safety or effectiveness.
TCO Wellness is a wellness and concierge-care company — we do not practice medicine. All prescriptions are issued by independent licensed physicians after review of your medical history, and medications are compounded and dispensed by a state-licensed 503A compounding pharmacy. Individual results vary.
Tirzepatide (B6/B12)
$39 consult + 30d coaching